49. Obstructive Sleep Apnea and Metabolic Syndrome; Causal Association or Co-Existence?
Ambreen Qamar1, Mirza Saifullah Baig2 and Nausheen Saifullah3
ABSTRACT
Objectives: To assess the association between Obstructive Sleep Apnea (OSA) and Metabolic Syndrome (MS).
Study Design: Case-Control study.
Place and Duration of Study: This study was conducted at Sleep Lab, Dow University Hospital, Karachi from February 2013 to November 2014.
Materials and Methods: The study was conducted on 100 individuals, 50 each of OSA subjects attending Sleep Lab in DUHS, Karachi and 50 controls. After informed consent and detailed history those having positive Epworth Sleep Scale (ESS) score went through full night polysomnographyto confirm their OSA and its severity. Appropriate correlations among components of MS and OSA were evaluated and analyzed applying SPSS version 20.
Results: The frequency of MS was 76% in OSA subjects compared to 48% in controls. Frequency of MS in mild, moderate and severe OSA was 50%, 82.4% and 85.7% respectively.
Conclusions: Our findings suggest that OSA is associated with a higher occurrence of MS; it was also associated with severity of OSA. Future research with larger sample size is advised to confirm these associations.
Key Words: Metabolic syndrome, Obstructive sleep apnea
Citation of article: Qamar A, Baig MS, Saifullah N. Obstructive Sleep Apnea and Metabolic Syndrome; Causal Association or Co-Existence? Med Forum 2017;28(4):188-192.