
4. Frequency and Clinico Pathological Features of Diffuse Large B Cell Lymphoma - A Tertiary Care Center Experience
Ambareen Hamid1, Sobia Ashraf1, Muhammad Azhar Farooq2 and Adil Iqbal3
ABSTRACT
Objective: To determine the frequency and study the clinicopaological features of DLBCL.
Study Design: Descriptive study
Place and Duration of Study: This study was conducted at the Department of Pathology, King Edward Medical University , Lahore from 2013 to 2017.
Materials and Methods: One hundred and seventy two consecutive cases of Non Hodgkins lymphoma referred for bone marrow biopsy were enrolled in the study. All the cases were diagnosed on histological biopsies. The patients receiving chemotherapy or radiotherapy were excluded from the study.
Results: Out of 172 patients 05 (2.9%) had T cell NHL and 167 ( 97.1%) had B cell lymphoma. Out of these B cell NHL 46 (26.7%) cases were of diffuse large B cell lymphoma. Cytopenias were observed in 32.6 % of patients. In 13 % patients bone marrow was infiltrated. The pattern of infiltration was diffuse.
Conclusion: DLBCL is a frequently presenting aggressive NHL having hcetrogenous clinical behavior.
Key Words: Clinico Pathological Features, Diffuse Large B Cell, Lymphoma
Citation of articles: Hamid A, Ashraf S, Farooq MZ, Iqbal A. Frequency and Clinico Pathological Features of Diffuse Large B Cell Lymphoma - A Tertiary Care Center Experience. Med Forum 2018;29(7):16-19.