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  3. 26. Incidence of Ovarian Cysts in Patients Taking Ovulation Induction with Clomiphene Citrate
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26. Incidence of Ovarian Cysts in Patients Taking Ovulation Induction with Clomiphene Citrate

Abroo Shahnaz1 , Joveria Sadaf1 , Asia Aziz2 , Tanzila Rafiq1 and Aslam Mahmood Malik1

Abstract

Objective: To determine the frequency of ovarian cyst in patients of induced ovulation.

Study Design: Descriptive study.

Place and Duration of Study: This study was conducted at the Department of Obstetrics & Gynecology, Shahida Islam Teaching Hospital Lodhran from September 2019 to August 2020.

Materials and Methods: A total of 214 patients with infertility planned for ovulation induction, 20-35 years of age were included. Patients with preexisting ovarian cyst were excluded. To all patients clomiphene citrate 50 mg was given from day 2 to day 6 of menstrual cycle. Serum progesterone levels were done on day 21 of cycle. If progesterone levels were > 30ng/dl then same dose of clomiphene citrate was given in next cycle. If day 21 progesterone levels were < 30 ng/dl then 100 mg of clomiphene citrate was given in 2nd cycle. In this cycle serum progesterone levels were done on day 21 and day 24. If progesterone levels were < 30 ng/dl then increments in the dose was made to a maximum dose of 150 mg per day in 3rd cycle. As part of protocol, in every patient transvaginal ultrasound was repeated before prescribing clomiphene citrate. Follicular tracking was added for monitoring of ovulation. After 3rd cycle pelvic ultrasound was done to diagnose any ovarian cyst.

Results: Age range in this study was from 20 to 35 years with mean age of 29.27 ± 2.34 years. Majority of the patients 132 (61.68%) were between 20 to 30 years of age. Mean duration of infertility was 3.81 ± 1.63 years. Mean BMI was 28.53 ± 2.59 kg/m2. Mean dose of clomiphene citrate was 84.63 ± 21.63 mg. Frequency of ovarian cyst in patients of induced ovulation was found in 22 (10.28%) patients.

Conclusion: This study concluded that frequency of ovarian cyst in patients of induced ovulation is quite high.

Key Words:  infertility, ovulation induction, ovarian cyst. Clomiphene citrate.

Citation of article: Shahnaz A, Sadaf J, Aziz A, Rafiq T, Malik AM. Incidence of Ovarian Cysts in Patients Taking Ovulation Induction with Clomiphene Citrate. Med Forum 2021;32(4):104-107.