9. Precipitating Factors of Hepatic Encephalopathy Experience at Shaheed Muhtarma Benazir Bhutto Medical University Larkana
Hakim Ali Abro, Azizullah Jalbani, Chandur Lal, Mumtaz Ali, Abdul Raheem and
Objective: To know the common precipitating factors and their frequency in patients presenting with Hepatic encephalopathy. The aims of this study were to evaluate the precipitant factors and analyze the treatment outcomes of HE in LC.
Study Design: Descriptive study
Place and Duration of Study: This study was conducted at the Medical Wards of Shaheed Mohtarma Benazir Bhutto Medical University Larkana from December 2017 to June 2018.
Materials and Methods: This study included all patients (age>12 years or both genders) with diagnosis of cirrhosis of liver presented with signs and symptoms for hepatic encephalopathy were included. Patients with acute hepatic encephalopathy were excluded from study. Detailed history and examination done and all patients were graded according to clinical criteria and investigation like CBC, viral marker, LFT, serum albumin, total protein, blood sugar, serum electrolyte coagulation profile, blood culture & ascitic fluid culture were carried out and abdominal ultrasound for signs of cirrhosis of liver and child pugh score were assessed in every patient. Data were entered in on preformed proforma.
Results: We surveyed 100 patients admitted with clinical diagnosis of hepatic encephalopathy, for one or more factors responsible for encephalopathy. The commonest precipitating factors were infections 58% upper gastrointestinal bleeding 48% and constipation were present in 44%. 40% patients have electrolyte imbalance,
22% have history of paracentesis, 10% have taken drugs like benzodiazepine and only 8% have taken the high protein diet.
Conclusion: Infection, GI bleeding, constipation and electrolyte imbalance were most common precipitating factors in our setup.
Key Words: Cirrhosis liver, precipitating factors, hepatic encephalopathy.
Citation of articles: Abro HA, Jalbani A, Lal C, Ali M, Raheem A, Ahmed S. Precipitating Factors of Hepatic Encephalopathy Experience at Shaheed Muhtarma Benazir Bhutto Medical University Larkana. Med Forum 2019;30(6):36-39.