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9. Clinical Features, Risk Factors, Imaging Characteristics and Outcome of Cerebral Sinus Thrombosis

Mohsin Khan1, Niama Khan2, Nisar Ahmad Khan3, Saif ud Din1, Haidar Zaman1 and Faizan Banaras1

ABSTRACT

Objective: To determine the presentation, clinical features, risk factors, imaging characteristics and outcome of patients with central venous sinus thrombosis.

Study Design: Cross-sectional study

Place and Duration of Study: This study was conducted at the Department of Medicine in Ayub Teaching Hospital Abbottabad from March 2022 to October 2022.

Materials and Methods: All patients carrying the diagnosis (based on magnetic resonance venography) of cerebral venous sinus thrombosis (CVST) will be included in study. The patient with arterial stroke, arteriovenous malformation, intra and extra cerebral hemorrhages, space occupying lesions, septic meningoencephalitis and autoimmune encephalitis will be excluded from study. The data collection tool will be written questionnaire and data will be analyzed in SPSS version21.

Results: In present study 62patients met the inclusive criteria. The mean age of females was 30years and males was 40 years. The most common features of CVST were headache (93%), followed by Seizures. The most common potential cause was puerperium (64%). On MRV superior sagittal sinus was found thrombosed in 48% cases and left transverse sinus in 45% of cases. The mean duration of hospital stay was 10 days.

Conclusion: Majority of postpartum females have significantly high white cell count, although only 06 patients had history of localized infection. Most of patients presented with headache and seizures. Intra parenchymal bleed or superior sagittal sinus thrombosis is suspected in patients who presented predominantly with seizures. Superior sagittal sinus is most commonly thrombosed sinus (59%) in patients who presented with seizures. Prognosis of CVST is favorable than previously reported.

Key Words: Cerebral venous sinus, thrombosis, seizures, outcome, risk factors

Citation of article: Clinical Features, Risk Factors, Imaging Characteristics and Outcome of Cerebral Sinus Thrombosis. Med Forum 2022;33(12):36-39.