8.Antibiogram of Bacterial Organism Isolated from Patients Admitted in ICU with Urinary Tract Infection
Rifat Yasmin1, Tazaeen Hina Kazmi1, Omer Dilawar2, Abdullah2, Aysha Rani1 and
Huma Hussain3
ABSTRACT
Objective: Identification of causative organism in severe urinary tract infections and their susceptibility to antibiotics which will make empirical therapy much easier to perform.
Study Design: Cross sectional study
Place and Duration of Study: This study was conducted at the Medical ICU, Pakistan Ordinance Factories Hospital, Wah Cantt from 1st June 2020 to 31st December 2021.
Materials and Methods: One hundred patients were enrolled. Samples were taken from blood and urine of the patient with severe UTI and sent to microbiologist for culture and sensitivity reports.
Results: The mean age was 59±15.5 years. Forty three were females and 57 were males. Thirty two died and 68 were shifted out. 28 were diagnosed with pyelonephritis, 54 urosepsis and 18 obstructive uropathy. Forty nine were E. coli positive, 27 Klebsiella pneumoniae, 13 Pseudomonas aeuriginosa, 5 Klebsiella oxytoca, 3 Proteus mirabillis and remaing 3 were serratia marcescens positive. Ciprofloxacin was sensitive in 25 patients, amikacin in 38 patients, piperacillin/tazobatam in 25 patients, cefoperazone/sulbactum in 24 patients, imipenem and meropenem in 34 and 23 patients respectively. Moxifloaxacin in 27 patients, nitrofutantoin 33 patients, colistin 55 patients and tigecycline in 36 patients were noted.
Conclusion: High levels of antibiotic resistance are seen among all gram negative bacterial isolates. Presence of elevated resistance to multiple drugs is an indicator for high prevalence of multi-drug resistant organisms, so proper identification of organism in order to ascertain administration of emperical drugs most effective against the isolated organism is recommended in severe cases.
Key Words: Antibiogram, Bacterial isolate, Pneumonia, Sensitivity
Citation of article: Yasmin R, Kazmi TH, Dilawar O, Abdullah, Rani A, Hussain H. Antibiogram of Bacterial Organism Isolated from Patients Admitted in ICU with Urinary Tract Infection. Med Forum 2022;33(10):34-39.