8. To Determine the Association of Neutrophil to Lymphocyte Ratio with Mortility and Outcome in Non St Elevation Myocardial Infarction, who Present to the Emergency Department of a Tertiary C
Muhammad Inam Qureshi1, Darshan Kumar2, Afzal Qasim3 and Muhammad Umar Khan2
ABSTRACT
Objectives: To determine the association of neutrophil to lymphocyte ratio with mortility and outcome in non st elevation myocardial infarction.
Study Design: Observational study.
Place and Duration of Study: This study was conducted at the Department of Emergency, Karachi institute of Heart Diseases and Dow University Health Sciences Karachi from 1st July 2016 to 31st December 2016.
Materials and Methods: This study consisted of two hundred thirty one patients. Detailed History was taken from all the patients with special regard to chest pain. Detailed Clinical examination of the patient was done. Systemic review was also done to see any co-morbidity. All patients underwent for base line and specific investigations. Patients aged 18 to 65 years, who have an NLR of >3.04 who present with signs and symptoms associated with NSTEMI and either gender were included in this study. Patients with a history of trauma, surgery, neoplasm, or infectious disease in the last 30 days prior to admissions. Patients currently using immunosuppressant (including corticosteroids) were excluded from study. Results were prepared with help of tables and graphs.
Results: Out of 231 patients included in this study 156(44.20%) males and 75(59.79%) females. Male : Female Ratio was 2.08:1. The mean age was 48.19+5.21 years. Most common risk factors were family history of CAD in 188(81.38%) cases and hypertension in 111(48.05%) cases. High Neutrophil to lymphocyte high ratio was present in 146(63.20%) patients while the low Neutrophil to lymphocyte ratio was in 85(36.79%) patients. Clinical outcome were observed hospital mortality were in 13(5.62%) and atrial fibrillation in 29(12.55%) cases and ST segment deviation were observed in 49(21.21%) cases.
Conclusion: We conclude that patients with Non ST Segment elevation Myocardial Infarction with high Neutrophil to lymphocyte ratio, is a good predictor of In hospital mortality, atrial fibrillation and ST segment deviation.
Key Words: Neutrophil To Lymphocyte Ratio, Non ST Elevation, Myocardial Infarction.
Citation of article: Qureshi MI, Kumar D, Qasim Am, Khan MU. To Determine the Association of Neutrophil to Lymphocyte Ratio with Mortility and Outcome in Non St Elevation Myocardial Infarction, who Present to the Emergency Department of a Tertiary Care Hospital of Karachi, Pakistan. Med Forum 2017;28(4):30-33.