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8. Do Vitamin D Levels Correlate with Stroke Severity? Study on Patients with Ischemic Stroke

Shazia Siddiq1, Sadia Hanif4, Jhangir Zaib1, Muhammad Nadeem1, Sadiq Hussain2 and Muhammad Fareed Khan3

ABSTRACT

Objective: To assess the vitamin D levels among patients presenting with acute ischemic stroke and relationship of these levels with severity of stroke.

Study Design: Cross-sectional study

Place and Duration of Study: This study was conducted at the Department of medicine, Sheikh Khalifa Bin Zayed Al-Nyhan  hospital Rawalakot, Eight months, from January 2020 to August 2020.

Materials and Methods: A total of 180 patients with ischemic stroke diagnosed by the consultant medical specialist on the basis of clinical and neuro-radiological findings were included in this study. Serum Vitamin D levels were assessed along with other baseline investigations among the study participants. Severity of stroke was assessed via National Institutes of Health Stroke Scale.

Results: Out of 180 patients of ischemic stroke included in the study 112 (62.2%) were male while 68 (37.8%) were female. On National Institutes of Health Stroke Scale, 98 (54.4%) had mild, 52 (28.8%) had mild to moderately severe, 20 (11.11%) had severe and 10 (5.56%) had very severe symptoms. 99 (55%) of the patients had Vitamin D levels within range while 81 (45%) had deficient vitamin levels.  Statistical analysis revealed that presence of hypertension and vitamin D deficiency had a statistically significant relationship (p-value <0.05) with severity of acute ischemic stroke.

Conclusion: Vitamin D levels were found low in significant number of patients presenting with acute stroke. Patients with Vitamin D deficiency and diagnosis of hypertension were more at chance of having severe symptoms of stroke as compared to those without diagnosis of hypertension and vitamin d deficiency.

Key Words: Ischemic stroke; severity; vitamin D

Citation of article: Siddiq S, Hanif S, Zaib J, Nadeem M, Hussain S, Khan MF. Do Vitamin D Levels Correlate with Stroke Severity? Study on  Patients with Ischemic Stroke. Med Forum 2021;32(3):34-37.