Search Submit Your Manuscript

Become A Member

  1. Home
  2. September 2023
  3. 7.Demographic Parameters of Patients Presenting with Chronic Myeloid Leukemia in Mayo Hospital Lahore. A New Epidemiological Addition
Article Image
Admin

7.Demographic Parameters of Patients Presenting with Chronic Myeloid Leukemia in Mayo Hospital Lahore. A New Epidemiological Addition

Hira Babar1, Zunairah Mughal1, Sobia Ashraf1, Nidda Ayub2, Hamna Arif1 and
Raana Akhtar1

ABSTRACT

Objective: To ascertain the demographic characteristics of patients diagnosed with Chronic Myeloid Leukemia.

Study Design: Cross Sectional study.

Place and Duration of Study: This study was conducted at the Pathology department of King Edward Medical University Lahore from January 2021 to January 2023

Materials and Methods: Two hundred and two patients diagnosed with Chronic Myeloid Leukemia according to WHO criteria were included in the study. Ultrasound abdomen was performed to estimate spleen size. Complete blood counts of all the patients were done for analysis of Hb, TLC, Platelet count, Basophils and Eosinophil percentage. Sokal score was noted. The phases of CML were compared with stratified groups and sokal score.

Results: Statistical analysis was done using SPSS version 22. Total 202 patients of CML in all phases were included in our study. Of 202 patients in total, the mean age was 42.24 ± SD. Male to female ratio was calculated as 1.83:1. A high percentage of 84.6% patients presented with chronic phase. Sokal score was low in 76.6% patients. 51.2% patients were seen having age more than 40 years, 65.7% patients belonged to rural areas. A positive association was seen with high sokal score and blast crisis whereas smoking did not show any significant correlation with patients.

Conclusion: The stratification of CML in various groups provided a helpful demographic data in our population. The comparison of different phases of CML with sokal score and demographic features helped in predicting the possible prognosis of the patients

Key Words: Chronic myeloid leukaemia, leukemia, epidemiology, CML, Philadelphia chromosomes

Citation of article: Babar H, Mughal Z, Ashraf S, Ayub N, Arif H, Akhtar R. Med Demographic Parameters of Patients Presenting with Chronic Myeloid Leukemia in Mayo Hospital Lahore. A New Epidemiological Addition. Forum 2023;34(9):28-31. doi:10.60110/medforum.340907.