7. Frequency of Peptic Ulcer Bleed in Cirrhotic Patients
Hamid Ullah1, Hashmatullah Khan2, Asfandyar Khan1, Abbas Masood1 and Mujahid Aslam2
ABSTRACT
Objective: To determine the frequency of peptic ulcer bleeds (PUB) in these patients.
Study Design: Retrospective descriptive study
Place and Duration of Study: This study was conducted at the Gastroenterology department of Qazi Hussain Ahmed Medical Complex, Nowshera and Lady Reading Hospital, Peshawar Khyber Pakhtunkhwa. The study period spanned from January 2018 till December 2023.
Methods: All In this retrospective study, cirrhotic patients above 12 years of age who presented with upper GI bleed and underwent upper GI endoscopy were included. Child-Pugh scoring system was employed for the classification of the severity of liver disease. All the analysis of collected data was done by employing IBM SPSS version 24.
Results: Totally, 166 cirrhotic patients with UGIB were included in this research. Variceal bleeding was seen in 89.2% of cases and peptic ulcer bleed was in 10.8% of the cases in our study. Bleed occurred predominantly in decompensated cirrhotic patients.
Conclusion: This study demonstrated the higher frequency of peptic ulcer bleeding in cirrhotic patients, highlighting the necessity for primary peptic ulcer prevention with a proton pump inhibitor in high-risk patients.
Key Words: peptic ulcer bleed (PUB), variceal bleed, upper gastrointestinal bleed (UGIB)