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7. Evaluate the Changes in Blood Chemistry and Types of Addiction during the Treatment of Patients of Head and Neck Cancer at Nuclear Institute of Medicine Radiotherapy, Jamshoro
Safia Shaheen1, Afsheen Mushtaque Shah1, Akhtar Hussain Samoo3, Naeem Ahmad Leghari2, Munawar Ali Kalhoro1, Raheela Qamar1 and Arshia Adeel4
ABSTRACT
Objective: To evaluate the Changes in Blood Chemistry and Types of Addiction during the Treatment of Patients of Head and Neck Cancer at Nuclear Institute of Medicine Radiotherapy, Jamshoro. Study Design: Observational / descriptive study.
Place and Duration of Study: This study was conducted at the Institute of Biochemistry, University of Sindh, Jamshoro in coordination with NIMRA and Ghulam Muhammad Mahar Medical Sukkur from June 2014 to December 2016.
Materials and Methods: Total 102 patients were selected with Head and Neck Cancer of grad III & IV. Specially designed questionnaire was used to collect the data, included age, sex, risk factors, sign symptoms, personal history, family history and histological diagnosis. Blood samples were collected and all parameters of Complete Blood Count (CBC) and Liver Function Test were performed.
Results: Majority of patients were between 41 to 50 years of age. 66.7% (n=68) patients 68 were male and 33.3% (n=34) were females founded, 65% (n=66) patients founded labor categories as occupation. Cheek was the most common site that affected as 44(43.1%) and second affected site was Tongue with 22 (21.6%) in all. Pain was most usually observed in 89 (87%) patients in Head and Neck region. Complete Blood Count (CBC) parameters were also disturbed during treatment as Lymphocytes, Monocytes, Basophils and Platelet Volume were (p<0.05) statistically significant. There was no significant variation (p>0.05) in Liver Function Test (LFT).
Conclusion: Due to lack of education and trend of tobacco used like Mainpuri and Naswaretc which slowly affect the health and most common cause. Efficiency of treatment and chance of persistence must be equally managed with latent practical and excellence of life time results. Patient's general situation and his or her capacity to bear forceful therapy must be considered by the cure team.
Key Words: Head and Neck Cancer, Chewing tobacco, Biochemical analysis
Citation of article: Shaheen S, Shah AM, Samoo AH, Leghari NA, Kalhoro MA, Qamar R, Adeel A. Evaluate the Changes in Blood Chemistry and Types of Addiction during the Treatment of Patients of Head and Neck Cancer at Nuclear Institute of Medicine Radiotherapy, Jamshoro. Med Forum 2017;28(6):24-28.