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5. Subclinical Hypothyroidism is More Common in Hyperglycemic Adult Overweight and Obese Individuals as Compared to Normoglycemics
Pervez Mohammad1, Mohammad Javed2 and Aurangzeb1
ABSTRACT
Objective: To know the significance of subclinical hypothyroidism in un-controlled diabetic adult overweight and
obese individuals in district Peshawar.
Study Design: Cross sectional study
Place and Duration of Study: This study was conducted at the Chemical Section of the Department of Pathology in Khyber Medical College Peshawar from April, 2015 to September, 2015
Materials and Methods: Two hundreds samples were collected by convenient sampling technique from general population of Peshawar district. The selected subjects were obese and overweight(BMI > 24.9 kg/m2) and of the age 18-50 years. Out of 200 subjects, 40 were female and 160 were male. Minimum age of the patient was 18 years and maximum age was 50 years. On the basis of age three groups were made, 18-28 years which included 40 patients 10 were female and 30 were male, age group between 29-40 years included 120 patients out of which 20 were female and 100 were male, age group 41-50 years included total number of 40 patients with 10 females and 30 males. 33 patients out of 200 had uncontrolled diabetes (DM-II). This included 26 male (13%) and 7 (3.5%) were female.
Results: The results are summarized in table 1 and 2. Whether plasma TSH levels were correlated with adiposity, we calculated Spearman Rank correlation of plasma TSH and BMI.In the results an inclination towards the association of plasma TSH level and body mass index was noted (r= 0.125, p= 0.078), while there is a substantial correlation between random blood sugar level and plasma TSH (r= 0.14, p= 0.046).Results showed that TSH level was elevated particularly in hyperglycemic overweight and obese subjects.This observation supports the view that SCH may be the result rather than an etiological factor for obesity and overweight.
Conclusion: The calculations of Spearman Rank correlation of plasma TSH and BMI show an inclination towards the association of plsma TSH level and body mass index (r= 0.125, p= 0.078), while there is a substantial correlation between random blood sugar level and plasma TSH (r= 0.14, p= 0.046).
Key Words: Subclinical hypothyroidism (SCH), Body mass index (BMI), thyroid stimulating hormone (TSH).
Citation of articles: Mohammad P, Javed M, Aurangzeb. Subclinical Hypothyroidism is More Common in Hyperglycemic Adult Overweight and Obese Individuals as Compared to Normoglycemics. Med Forum 2017;28(10):21-24.