5. Blood Culture Positivity in Acute Pyogenic Meningitis
Jan Muhammad Afridi, Yasir Rehman, Arshia Munir and Qamar Ali
ABSTRACT
Objective: To compare CSF Culture VS Blood Culture in 88 Patients Newly Diagnosed as Acute Septic Meningitis Admitted in Paediatrics Department KTH.
Study Design: Descriptive / cross-sectional study
Place and Duration of Study: This study was conducted at the Department of Pediatrics, Khyber Teaching Hospital, Peshawar from June 2017 till December 2017.
Materials and Methods: 88 patients presenting with clinical signs and symptoms of acute septic meningitis were selected through non randomized convenient sampling. Before enrolling the patients informed consent was taken from the attendant. For every patient a proper record was maintained on a standardized proforma. Detailed history and examination was done with a special emphasis on signs and symptoms suggestive of meningitis were documented. Lumber puncture was performed under aseptic technique and samples were sent for analysis and culture to the Khyber Medical College Pathology Department. Where the CSF culture was performed by Beckitic Machine using special culture bottle and the results were received and interpreted.
Results: Out of 88 patients with meningitis 7 patients (7.9%) had positive CSF Culture. 10 patients had staphylococcus Epidermidis growth which was considered contamination. Out of 7 positive culture 3 patients (3.4%) had MRSA positive CSF Culture, 2 patients (2.2%) had Staphylococcus Aurius and 1 patient (1.1%) each had Streptococcus Pneumonie and E.Coli in CSF Culture.
Out of 88 patients with meningitis 6 patients (6.8%) had positive blood culture. 8 patients had staphylococcus Epidermidis growth which was considered contamination . Out of 6 positive culture 2 patients (2.2%) had MRSA positive blood Culture, 1 patient (1.1%) each had Staphylococcus Aurius,Streptococcus Pneumonie, Psudomonas and E.Coli in Blood Culture.
Conclusion: In our study it was found that MRSA is the commonest cause of septic meningitis comprising 3 (3.4%) patients followed by Staphylococcus Aurius in 2 (2.2%) and 1 (1.1%) patient each had Streptococcus Pneumonie and E.Coli. Similar results of blood culture were seen with commonest growth of MRSA found in 2 (2.2%) patients followed by 1 (1.1%) patient each of Staphylococcus Aurius,Streptococcus Pneumonie, Psudomonas and E.Coli .
Septic meningitis is a serious condition and inappropriate or delay in the management may result in serious fatal complications therefore aggressive and appropriate antibiotic therapy is vital for better outcome.
Key Words: Acute Pyogenic Meningitis, Cerebrospinal fluid (CSF)
Citation of articles: Afridi JM, Rehman Y, Munir A, Ali Q. Blood culture positivity in Acute Pyogenic Meningitis. Med Forum 2018;29(7):20-24.