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Antibiotic Sensitivity and Resistance Patterns of Common Microbes among Burn Patients at Ayub Teaching Hospital, Abbottabad

Firdous Khan, Abdullah Mahmood and Saad Iqbal

ABSTRACT

Objective: To determine the most frequently occurring microbes in burn infections, along with their antibiotic sensitivity and resistance profile and to revise treatment protocols accordingly.

Study Design: Descriptive cross- sectional study

Place and Duration of Study: This study was conducted at the Department of Plastic Surgery & Burns, Ayub Teaching Hospital Abbottabad from 1^st January 2024 to 30^th June 2024.

Methods: This descriptive cross-sectional study included 97 patients with burn injuries having a Total Burn Surface Area (TBSA) greater than 10% and who had not been previously treated. Data were collected using a non-probability consecutive sampling technique after obtaining informed consent. Microbial analysis was performed and data were analyzed. Pearson chi-square test was applied and P value ≤ 0.05 was considered significant.

Results: Mean age of patients was 33.3 years. Out of 97 patients, majority of cases were seen in females (58.8%). Methicillin Resistant Staphylococcus Aureus (MRSA) and Pseudomonas Aeruginosa were the most commonly isolated organisms (34% and 30.90%) respectively. Linezolid (68%) and Meropenem (58%) are the most sensitive antibiotics while Amoxicillin-Clavulanic acid and Erythromycin carries the highest resistance rate i.e. 93.8%
for both.

Conclusion: There is a rising concern of multidrug resistant organisms especially Pseudomonas Aeruginosa and MRSA. Several antibiotics like Piperacillin, Tazobactum, and Meropenem are becoming more and more resistant. Some drugs like Linezolid and Vancomycin still have better efficacies but they should be used cautiously.

Key Words: Burn injury, Sensitivity, Multidrug resistant organisms

Citation of article: Khan F, Mahmood A, Iqbal S. Antibiotic Sensitivity and Resistance Patterns of Common Microbes among Burn Patients at Ayub Teaching Hospital, Abbottabad. Med Forum 2024;35(8):22-26. doi:10.60110/medforum.350805.