47. Frequency of Bacteria Causing Urinary Tract Infections During Pregnancy and Antimicrobial Sensitivity in Southern Punjab-Pakistan
S. M. Abbas Naqvi, M. Majid Rasheed, Shahbaz Anwar, Rubina Yaseen and Muhammad Nouman Iqbal
ABSTRACT
Objective: Urinary tract infections are common infection and incidence resistant strains causing UTI is also increasing. Bacteriuria results in serious complications in mother and fetus. The need of the hour is to aware the pregnant women of proper screening and improved treatment against resistant bacteria.
Study Design: Descriptive Cross-sectional study
Place and Duration of Study: This study was conducted at the Department of Pathology in collaboration with the Gynecology department, Nishtar Medical College/Hospital, Multan from October 2018 to February 2019.
Materials and Methods: One hundred and sixty (n=160) pregnant women, presenting with signs and symptoms of UTI, were included in the study from Gynaecology outdoor of Nishtar Hospital, Multan. Midstream urine samples were collected in sterile containers and processed in microbiology section of that college. Complete urine examination and urine culture were done to diagnose UTI. Antimicrobial susceptibility testing of isolated bacteria were also done by standard Kirby-Bauer disk diffusion method using CLSI 2015 guidelines.
Results: Out of total 160 urine samples, 58 samples were culture positive. Of all isolates (100% i.e., 58), the highest number was of Staphylococcous aureus 41.38% (n=24) followed by E. coli 29.31% (n=17), S. saprophyticus 10.34% (n=6), Klebsiella enterica 5.18% (n=3), Pseudomonas spp 5.17% (n=3), Enterococcous fecalis 3.45% (n=2), Enterobacter spp 3.45% (n=2) and Staphylococcous epidermidis 1.69% (n=1). Moreover, 23.5% of Multi drug resistant E. coli were also isolated.
Conclusion: The study concluded that Staphylococcous aureus and Escherichia coli were the most frequent organisms isolated, with 23.5% of multidrug resistant E. coli. It is suggested, considering the complications of UTIs, that every pregnant women should have regular screening for bacteriuria followed by antibiotic susceptibility testing for improved therapy against resistant organisms.
Key Words: UTI. Pregnant women, Multidrug Resistant E. Coli, Staphylococcous Aureus.
Citation of article: Naqvi SMA, Rasheed MM, Anwar S, Yaseen R, Iqbal MN. Frequency of Bacteria Causing Urinary Tract Infections During Pregnancy and Antimicrobial Sensitivity in Southern Punjab-Pakistan. Med Forum 2020;31(9):203-206.