44. Effectiveness of Magnesium Sulfate for the Treatment of Severe Traumatic Brain Injury
Naeem ul Haq, Muhammad Ishaq, Musawer Khan and Adnan Ahmed
ABSTRACT
Objective: The aim of this study is to determine the effectiveness of magnesium sulfate for the treatment of severe traumatic brain injury.
Study Design: Prospective study
Place and Duration of Study: This study was conducted at the Neurosurgery Unit Mardan Medical Complex, Mardan for duration of one year from 1st November 2019 to 31st October, 2020.
Materials and Methods: Total 70 patients of both genders were included in this study. Enrolled patients were aged between 20-65 years. Patients detailed demographics age, sex and body mass index were recorded after taking written consent. Glasgow coma score (GCS) were recorded in this research at first day of admission in hospital and at the 5th day. Complete data was analyzed by SPSS 24.0 version.
Results: Out of 70 patients 50 (71.43%) patients were males and 20 (28.67%) patients were females. Mean age of the patients were 41.38 ± 7.87 years with mean BMI 27.12 ± 8.25 kg/m2 . Mean duration of the post traumatic brain injury was 7.68 ± 4.32 hours. Mean GCS without magnesium sulfate at first day was 7.46 ± 2.32 but at the 5th day GCS was 11.41 ± 1.56. Significantly difference was observed with p value < 0.0126. But significantly difference was not observed in GCS with respect to gender and duration of disease.
Conclusion: We concluded in this study that use of magnesium sulfate was effective for the treatment of traumatic brain injury among patients. GCS among patients were improved by using magnesium sulfate at the 5th day.
Key Words: Magnesium Sulfate, traumatic brain injury, Glasgow Coma Score (GCS)
Citation of article: Haq NU, Ishaq M, Khan M, Ahmed A. Effectiveness of Magnesium Sulfate for the Treatment of Severe Traumatic Brain Injury. Med Forum 2021;32(3):181-183.