41. Hematological Changes in Patients Presenting with Pulmonary Tuberculosis
Shah Taj Khan1, Muhammad Abbas2, Subhan Uddin3, Awal Mir4, Babar Rehman1 and
Hamid Ullah2 ABSTRACT
Objective:To evaluate hematological changes in Pulmonary Tuberculosis (TB).
Study Design:Observational / descriptive / cross sectional study.
Place and Duration of Study: This study was conducted in Pathology Department, Hayatabad Medical Complex Peshawar from Nov 2015 to Oct 2016.
Materials and Methods:In the present study a total of 150 subjects were enrolled, out of them 100 patients diagnosed as pulmonary TB and 50 as control healthy individuals. Pulmonary tuberculosis was diagnosed by direct sputum smear microscopic examination after Ziel Nelson stain. Blood counts were performed on all these patients by hematology analyzer (CD Rubby, Abbott, USA) and ESR was also performed for all these patients by Westergren method.
Results:In the present study 35% had anemia with hemoglobin level was 10 ± 867 gm/dl. In 15% Patients had leucopenia with TLC was 2.5±1.567×103/µl and 12% patients had leukocytosis, TLC was 18±1.565×103/µl. 10% patients had thrombocytosis, Platelet count was 480±20.545×103/µl and 8% patients had thrombocytopenia with platelet count was 120±118.3 ×103/µl. ESR were 100 ±10 mm/1st hour for all the patients. These values were significantly changed as compared to control values.
Conclusion:The study concludes that pulmonary Tuberculosis is significantly associated with hematological abnormalities. The patients presenting with cytopenia or cytosis the physician must have suspicious of the disease and he should immediately screen the patient for pulmonary tuberculosis. This will reduce unnecessary procedure of bone marrow aspiration and will provide prompt treatment to the patient and reduced complication and spread to the community.
Key Words:Pulmonary TB, Anemia, Leukopenia, Leukocytosis, Thrombocytosis, Thrombocytopenia.
Citation of article:Khan ST, Abbas M, Uddin S, Mir A, Rehman B, Ullah H. Hematological Changes in Patients Presenting with Pulmonary Tuberculosis.Med Forum 2017;28(5):166-169.