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4. Pregnant Females with Polycystic Ovary Syndrome (PCOS) and Effect of Metformin Against Gestational Diabetes Mellitus
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Original Article |
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Effect of Metformin Against Diabetes Mellitus In Pregnant |
Pregnant Females with Polycystic Ovary Syndrome (PCOS) and Effect of Metformin Against Gestational Diabetes Mellitus
Sohail Bashir Sulehria1, Sohail Anjum2 and Ghulam Murtaza Hiraj3
ABSTRACT
Objective: To study effect of metformin against diabetes mellitus in pregnant females with PCOS
Study Design: Descriptive cases series study.
Place and Duration of Study: This study was conducted at the Kishwar Fazal Teaching Hospital of Amna Inayat Medical College Lahore Period February 1, 2023 to July 31, 2023.
Methods: A follow up of two hundred pregnant women was done for absence or presence of Gestational Diabetes Mellitus until they got delivered. On pre-designed form, efficacy frequency in women having PCOS was recorded. The data analysis was done using Statistical Package of Social Services version 25.
Results: In one hundred sixty six women (83%) metformin efficacy got achieved. On the other thirty four (17%) women could not get efficacy. Seventy one (84.52%) was efficacy for age group between twenty to thirty years. Ninety eight (84.48%) was efficacy for age group between thirty one to forty years. Regarding patient’s B.M.I (Body Mass Index) stratification of data was performed. Eighty four (100%) was efficacy for those having normal weight. Sixty five (93%) was efficacy for overweight patients. Thirty nine (59%) was efficacy for obese patients.
Conclusion: In 83% pregnant women metformin for control of plasma sugar had been proved to be effective. Moreover metformin recommendation suggested for PCOS resolution in pregnant women to stay away from GDM. Prevalence, Gestational Diabetes Mellitus, Pregnant Females, PCOS, Metformin, Efficacy
Key Words: Pregnant Females, Polycystic Ovary Syndrome (PCOS), Gestational Diabetes Mellitus