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Rasheed Ahmed Soomro¹, Asim Mehmood², Samreen Ali³, Muhammad Atif Ata⁴, Jawad Mumtaz Sodhar⁵ and Umair Ali Soomro⁶

ABSTRACT

Objective: To study and correlate vitamin D and uric acid among general population of Sindh.

Study Design: Cross sectional study

Place and Duration of Study: This study was conducted at the Suleman Roshan Medical College, Tando Adam, Sindh from January 2020 to August 2021.

Materials and Methods: A sample of 700 normal healthy subjects of both genders was selected according to pre – determined criteria. Volunteers, age (40 – 60 years), both genders were inclusion criteria. Physical examination was performed, and blood samples were collected to estimate the vitamin D and serum uric acid. Data was analyzed using student t – test for continuous variables and Chi – square test for categorical variables. Pearson`s correlation was used to determine correlation of vitamin D and uric acid. SPSS ver. 20 analyzed data variables at 95% confidence interval (P≤0.05).

Results: Vitamin D was found very low 27.05±14.4 ng/dl in male and 15.7±8.51 ng/dl in female (P=0.0001). High uric acid was noted in both male and female subjects; 7.60±1.38 and 6.47±2.36 mg/dl respectively (P=0.0001). Vitamin D deficiency and sufficiency was noted in 75.4% (14.4186±5.1 ng/dl) and 24.5% (42.7±4.1 ng/dl) (P=0.0001). Serum uric acid normal and high levels were found in 173 (24.7%) and 527 (75.2%) respectively (P=0.0001). Vitamin D shows significantly strong negative correlation with serum uric acid (r=-0.852, p=0.0001). Negative correlation of vitamin D and uric acid in male was (r=-0.706, p=0.0001) and in female (r=-0.892, p=0.0001).

Conclusion: The present study observed strong negative correlation of vitamin D and serum uric acid in normal adult healthy subjects.

Key Words: Vitamin D, Uric acid, Correlation, Sindh

Citation of article: Soomro RA, Mehmood A, Ali S, Ata MA, Sodhar JM, Soomro UA. Correlation of Vitamin D and Uric Acid among General Population of Sindh. Med Forum 2022;33(1):9-12.