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Beenish Samreen Hamid¹, Tajwar Sultana², M Irfan ul Akbar Yousufzai³, Fouzia Qadir⁵, Rana Tauqir Ullah Khan⁴ and Muhammad Shereen⁵

ABSTRACT

Objective: The objective of this study to evaluate efficacy of progesterone in women with threatened miscarriage in Kohat.

Study Design: Case-Control study

Place and Duration of Study: This study was conducted at the Obstetrics and Gynecology KMU-IMS Kohat and Department of Pharmacology Muhammad College of Medicine's Peshawar from February 2020 to January 2021 for a period of 11 months.

Materials and Methods: Patients in the Test Group (Oral progesterone) ranging in age from 30.54 to 10.48 year. Patients in the Control Group (no progesterone) ranged in age from 30.55 to 10.38 years old. All of the women were given a thorough medical history and examination. Women were divided into two groups at random: test and control. The absence of vaginal bleeding was used to measure efficacy.

Results: A total of 210 women (105 in each group) were examined in this trial, with patients in the Test Group (Oral progesterone) ranging in age from 30.54 to 10.48 year. Patients in the Test Group (no progesterone) ranged in age from 30.55 to 10.38 years. Because Control Group (Oral progesterone) was effective in 91 (95.55 %) patients and Control groups resulted in 5 (5.25%) patients, Efficacy was measured in terms of absence of vaginal bleeding.

Conclusion: Oral progesterone was found to be more efficacious than placebo in reducing threatening miscarriages in the first trimester. Our findings suggest that progesterone medications are helpful in preventing miscarriage in women who are at risk of miscarriage.

Key Words: Oral progesterone, threatened miscarriage

Citation of article: Hamid BS, Sultana T, Yousufzai MIA, Qadir F, Khan RT, Shereen M. Evaluation of Progesterone Efficacy in Women with Threatened Miscarriage in Kohat. Med Forum 2021;32(10):155-158.