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34. To Determine the Efficacy of Polyethylene Glycol in the Treatment of Pediatric Constipation

Original Article

Polyethylene Glycol in the Treatment of Pediatric Constipation

To Determine the Efficacy of Polyethylene Glycol in the Treatment of Pediatric Constipation

Muhammad Owais, HameedUllah, Iftikhar Khanand Zeeshan Ahmad

ABSTRACT

Objective:To assess the efficacy of polyethylene glycol (PEG) in treating pediatric constipation and provide local statistics for improved clinical decision-making and recommendations on future treatment strategies.

Study Design:Randomized Controlled Trial(RCT)

Place and Duration of Study: This study was conducted at thedepartment of Women and Children Hospital from January 2023 to January 2024.

Methods:A descriptive case series was conducted with 146 pediatric patients over six months. Children aged 4 years and older underwent clinical examinations, including abdominal and rectal assessments. Polyethylene glycol (PEG 3350) was administered at 1.5 g/kg/day as a single dose for four weeks. Treatment efficacy was evaluated at the end of the 4th week.

Results:The mean age of the patients was 8 years (SD ± 6.34). Of the 146 participants, 58% were male, and 42% were female. Polyethylene glycol was effective in 72% of the patients. The p-value for the efficacy of treatment was statistically significant (<0.05), indicating that PEG was an effective treatment option for most patients.

Conclusion:Polyethylene glycol demonstrated significant efficacy (72%) in managing pediatric constipation. The findings highlight its effectiveness as a primary treatment option. Future research should focus on long-term outcomes and alternative dosages for children who do not respond to initial treatment.

Key Words:Efficacy, polyethylene glycol, constipation, pediatric

Citation of article:Owais M, Ullah H, Khan I, Ahmad Z.To Determine the Efficacy of Polyethylene Glycol in the Treatment of Pediatric Constipation.Med Forum2024;35(12):156-159.doi:10.60110/medforum.351234.