34. Study on Association Between Severity of Childhood Asthma and Serum Vitamin D Levels in Children 1 to 12 Years of Age
Ghulam Shabir Laghari, Saeed Ahmed Shaikh, Abdul Hameed Radhan, Muhammad Touseef, Saroop Chand and Mushtaque Ali Shah
ABSTRACT
Objective: To assess serum Vitamin D levels in 100 Asthmatic children 1-12 years of age and to study the relation between Vitamin D levels and the severity of asthma.
Study Design: Cross-sectional study.
Place and Duration of Study: This study was conducted at the Department of Pediatrics, Liaquat University of Medical and Health Sciences Jamshoro for one year 1st December 2019 to 30th November 2020.
Materials and Methods: This study was done in 100 asthmatic children diagnosed and Vitamin D levels were assessed. Vitamin D levels <20ng/dl were taken as deficient levels, 21-29 as insufficient levels, and more than 30 as sufficient levels.
Result: Fifty-four (54%)of asthmatic children had vitamin D deficiencies and 17% had inadequate levels. Deficient Vitamin D levels were found in 41% of children with intermittent asthma, 58% of children with mild persistent asthma, and 56 % of children with moderate persistent asthma whereas insufficient levels of Vitamin D were found in 18% of the children with intermittent asthma, 16% with mild persistentasthma and 19% with moderate persistent asthma. It was also found that nasal eosinophilia was associated with increased severity of asthma and children with nasal eosinophilia had a higher risk for persistent asthma.
Conclusions: A high prevalence of Vitamin D deficiency and insufficiency was found in asthmatic children studied. No association between the deficit in vitamin D and the severity of asthma was discovered.
Key Words: Asthma; Vitamin D; Children, Severity
Citation of article: Laghari GS, Shaikh SA, Radhan AH, Touseef M, Chand S, Shah MA. Study on Association Between Severity of Childhood Asthma and Serum Vitamin D Levels in Children 1 To 12 Years of Age. Med Forum 2021;32(6):137-141.