34. An Experience of Treatment Outcome in Acute Appendicitis with Antibiotics and Appendectomy at a Tertiary Care Hospital
Gulshan Ali Memon1, Amir Iqbal Memon2, Syed Kashif Ali Shah1, Rafiq Ahmed Sahito1,
Habib-ur-Rehman1, Shahnawaz Leghari1 and Shahida Baloch1
ABSTRACT
Objective: The present study was designed with an objective to assess the outcomes of antibiotics as primary treatment versus appendectomy in uncomplicated acute appendicitis (UAA).
Study Design: Observational study
Place and Duration of Study: This study was conducted at the Department of Surgery, PUMHSW Nawabshah from 2014 to April 2016.
Materials and Methods: A sample of 227 diagnosed cases of acute appendicitis of both genders, age 16 - 60 years, clinical history and clinical signs of appendicitis with positive findings on Ultrasonography and increased leukocyte counts were the inclusion criteria. Study subjects were divided into group A and B on the basis of modified Alvarado score. Patients <4 score Alvarado score was exclusion criterion. Data was analyzed on SPSS 22.0 (P≤0.05).
Results: During of pain and analgesic consumption was significantly higher in the group B as compared to group A in initial 2 days after surgery (p=0.001). However, the intensity of pain started decreasing after 2 days in group A and 4 days in group B, and this difference disappeared at one-month follow up. Hospital stay was lengthy in group B and surgical site infections were comparatively higher in group A patients. Mean cost therapy was expensive in group B compared to group A.
Conclusion: The present study concludes the antibiotic therapy as safe and effective alternate to appendectomy in uncomplicated acute appendicitis with low recurrence rate and cost.
Key Words: Acute appendicitis, Appendectomy, Antibiotic treatment
Citation of article: Memon GA, Memon AI, Shah SKA, Sahito RA. Rehman H, Leghari S, Baloch S. An Experience of Treatment Outcome in Acute Appendicitis with Antibiotics and Appendectomy at a Tertiary Care Hospital. Med Forum 2017;28(3):136-140.