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31. Association of Anti-Tissue Transglutaminase Antibodies with Intestinal Damage in Celiac Disease

Tayyaba Mubeen, Muhammad Aamir Adnan, Anam Bilal and Muhammad Sulaiman Saeed

ABSTRACT

Objective: To study the prevalence of celiac disease in different age groups ranging from 07 months-22 years  in Multan and its periphery and the role of anti-tissue transglutaminase antibodies in the diagnosis of celiac disease.

Study Design: Descriptive / cross sectional study

Place and Duration of Study: This study was conducted at the Nishtar Medical College and Hospital Laboratory Multan from January 2016 to June 2016.

Materials and Methods: This study was conducted on 178 patients received at Nishtar medical unit III, both male and females, from the age group 07 months to 22 years with the suspicion of celiac disease(CD). All duodenal biopsy cases, in whom anti-tissue transglutaminase antibody test was conducted prior to duodenal biopsy, referred to Nishtar medical college and hospital laboratory Multan from the January 2016 to June 2016 were reviewed.All data was entered and analyzed by using statistical software SPSS version 23.1. Mean ± SD calculated for numerical data and categorical data was presented as frequency and percentages. Chi square test was applied to see effect

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