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30.Frequency of ABO Incompatibility in Neonates Presenting with Unconjugated Hyperbilirubinemia

Saqib Munir1, Samia Ijaz1, Mimpal Singh1, Ayesha Abdul Kareem2 and Kashif Mehmood1

ABSTRACT

Objective: To find the frequency of ABO incompatibility in newborns presenting with neonatal jaundice.

Study Design: Cross sectional study

Place and Duration of Study: This study was conducted at the Medicine Unit II, Pediatric Department, Mayo Hospital, Lahore from November, 2017 to May, 2018.

Materials and Methods: 100 neonates who fulfill the inclusion criteria were included in the study. Then blood sample was obtained by using pricker from foot and three drops will be obtained. Antigens A & B was applied and blood group of neonate was noted. Blood group of mother was also assessed. If blood group of neonate was A, B or AB and blood group of mother was O, then ABO incompatibility was labeled. All data was entered in specially designed Performa. The data was analyzed through SPSS version 21.

Results: The neonates mean age was 16.53±9.99 hours. There were 59 (59%) male and 41 (41%) female neonates. The mean gestational age of neonates at birth was 37.67±1.71 weeks. The mean birth weight of neonates was 2354.58±379.16 grams. The mean unconjugated bilirubin level was 7.55±1.45 mg/dl. There were 28 (28%) had ABO incompatibility.

Conclusion: Thus the frequency of ABO incompatibility was high in neonates with hyperbilirubinemia. So ABO incompatibility can be a risk factor for neonatal hyperbilirubinemia.

Key Words: ABO incompatibility, neonates, neonatal jaundice, hyperbilirubinemia

Citation of article: Munir S, Ijaz S, Singh M, Kareem AA, Mehmood K. Frequency of ABO Incompatibility in Neonates Presenting with Unconjugated Hyperbilirubinemia. Med Forum 2021;32(8):133-136.