1. Babar Bashir 2. Akhtar Ali Baloch 3. Jawwad us Salam 4. Munir Hussain Siddiqui 

5. Pyar Ali Fazel 6. Mohammad Masroor

1. Assoc. Prof. of Medicine, SMBB Medical College, Karachi 2. Prof. of Medicine, DUHS, Karachi 3. Asstt. Prof.

of Neurology, DUHS, Karachi 4. Assoc. Prof. of Medicine, DUHS, Karachi 5. Asstt. Prof. of Medicine, DUHS, Karachi 6. Prof. of Medicine, Principal, DIMC, DUHS, Karachi 

ABSTRACT

Objective: To determine the frequency of impaired glucose tolerance in patients presenting with active pulmonary tuberculosis in tertiary care hospital, Karachi.

Study Design: Cross sectional study.

Place and Duration of Study: This study was conducted at Dow University Hospital (Dow University Health Sciences Karachi) from 1^st June 2014to 30^th November 2014.

Materials and Methods:  A total of 110 diagnosed adult cases of active pulmonary tuberculosis on the basis of sputum smear positivity were included in this study. Blood samples were drawn for investigations and sent to the same reference laboratory to minimize bias.  Data was collected on a pre-tested self administered Performa. Results: There were 59.1% were male and 40.9% were female.  Frequency of impaired glucose tolerance in patients presenting with active pulmonary tuberculosis was observed in 20.9%.  Rate of impaired glucose tolerance was highly associated with above 40 years of age patients and with family history of diabetes. 

Conclusion:  In Pakistan DM is on the rise and TB has one of the highest incidence in the world. There is emerging evidence that one disease is fuelling the other. The interest in diabetes and TB is mounting rapidly, so the clinician & researchers should prepare themselves to meet the challenges of the two disease combined.

Key Words: Impaired glucose tolerance, pulmonary tuberculosisand diabetes mellitus

Citation of article: Bashir B, Baloch AA, Salam J, Siddiqui MH, Fazel PA, Masroor M. Frequency of Impaired Glucose Tolerance Test in Patients with Active Tuberculosis. Med Forum 2015;26(12):11-16.