3. Effects of Intra-Cameral Dexamethasone after Uncomplicated Phacoemulsification
Muhammad Saad Ullah, Muhammad Usama Rahim and Hassan Shoaib
ABSTRACT
Objective: To assess the efficacy of administering dexamethasone through intra-cameral injection in comparison to the conventional application of topical steroids for individuals undergoing phacoemulsification.
Study Design: Quasi experimental trial study
Place and Duration of Study: This study was conducted at the department of Ophthalmology Ghazi Hospital Dera Ghazi Khan form September 2022 to August 2023.
Methods: Eighty patients of age 55-80 years were enrolled in the study and divided into two groups 1 and 2. In group 1 patient were given intra-cameral dexamethasone and in group 2 equal amount of 0.01 ml normal saline was administered.
Results: At 1st post-operative day mean IOP in group 1 was 14.75±2.55 and in group 2 was 17.85±2.22. Similarly, at day 7 mean IOP in group 1 was 13.18±2.14 and in group 2 it was 12.44±1.74. In comparison pre operative IOP was in group 1 and 2 was 16.19±2.54 and 12.44±1.74 respectively.
Conclusion: Intraoperative inflammation following phacoemulsification surgery can be effectively managed by administering intra-cameral dexamethasone injection, resulting in decreased flare and anterior chamber cells, with comparable impacts on IOP and visual acuity when compared to the use of topical steroids.
Key Words: Dexamethasone, Effectiveness, Intra ocular pressure, Intra-cameral injection, Phacoemulsification.