3. Clinicopathological Profiles of Lymph Node Enlargement at Mayo Hospital, One Year Study
Samina Qamar, Shahid Mahmood, Ahmad Hameed and Sobia Ashraf
ABSTRACT
Objective: This study aimed at evaluating the causes of lymphadenopathy and demographic distribution of patient load at mayo hospital, Lahore.
Study Design: Descriptive / cross-sectional study.
Place and Duration of Study: This study was conducted at the Pathology Department King Edward Medical University/ Mayo Hospital, Lahore from January 2016 to December 2016.
Materials and Methods: All lymph node biopsies were reviewed at histopathology section of Pathology Department King Edward Medical University/ Mayo Hospital, Lahore. Demographic details of patients, site of lymph node enlargement and diagnoses of lymph node biopsy were recorded on proforma. SPSS 21 and descriptive statistics were used to obtain results of age, gender, site of lymphadenopathy, residential address and diagnoses were evaluated.
Results: Total of 308 cases were included in study. Most common cause was reactive hyperplasia 218(70.8%), 56 (18.2%) showed Tuberculosis, 14 (4.5%) exhibited metastatic carcinoma, 9 (2.9%) were labeled as Atypical lymphoprolifertaive disorder, 6 (1.9%) were of Non-Hodgkin lymphoma, 3 (1.0%) of Hodgkin lymphoma and 2 (0.6%) of abscess. 206(66.9%) patients were from Lahore, 43 (14.0%) from Sheikhupura, 19 (6.2%) from Narowal, 17 (5.5%) from Nankana, 11(3.6%) from Okara, 7(2.3%) from Mianwali and 5 (1.6%) belonged to Bahawalnagr.
Conclusion: Reactive lymph node enlargement is most common cause of lymphadenopathy in tertiary care setup. Tuberculosis is second most common cause, seen more in females. Mayo Hospital is catering a large number of patients from cities other than Lahore. It is suggested that tertiary care services should be strengthened in areas surrounding Lahore to lower patient burden and improve health facilities at Mayo Hospital. Government hospitals should be equipped with special tests like immunomarkers and molecular techniques to precisely diagnose lymphoid malignancies.
Key Words: Atypical Lymphoproliferative disorder, Demographic, Hodgkin Lymphoma, Lymphadenpathy, Non-Hodgkin Lymphoma, Tuberculosis.
Citation of articles: Qamar S, Mahmood S, Hameed A, Ashraf A. Clinicopathological Profiles of Lymph Node Enlargement at Mayo Hospital, One Year Study. Med Forum 2018;29(11):10-14.