2.Frequency and Association of Subclinical Thyroid Disorders with Poor Obstetric Outcome
Sumaira Yasmin and Farnaz Zahoor
ABSTRACT
Objective: To determine the frequency and association of subclinical thyroid disorders in patients with poor obstetric outcomes.
Study Design: Cross sectional study
Place and Duration of Study: This study was conducted at the Department of Obstetrics and Gynecology, Lady Reading hospital Peshawar from August 2019 till July 2020.
Materials and Methods: Women of reproductive age with a bad obstetrical history during her visit in the outpatient department of the hospital were enrolled. Obstetrical details including previous miscarriages, stillbirths, neonatal deaths and congenital anomalies were recorded by interviewing the patient as per questionnaire. patients fulfilling the inclusion criteria were subjected to thyroid function tests. Data was analyzed on SPSS version 18.
Results: Out of the 549 women presenting with a poor obstetric outcome, 103women were recruited for the study. subclinical thyroid disorders were found to be 24.27%, with subclinical hypothyroidism more prevalent (21.35 %) in patients with poor obstetric outcome. significant weak positive correlation was reported between neonatal deaths and TSH levels (r= 0.200; p= 0.043).
Conclusion: Subclinical thyroid dysfunction is more prevalent in patients with poor obstetric outcome. various adverse fetal and neonatal outcomes are expected to be encountered in patients with subclinical thyroid dysfunction.
Key Words: Subclinical hypothyroidism, thyroid stimulating hormone, miscarriage, stillbirth
Citation of article: Yasmin S, Zahoor F. Frequency and Association of Subclinical Thyroid Disorders with Poor Obstetric Outcome. Med Forum 2021;32(7):7-10.