2.Efficacy of Evening Primrose Oil in Treatment of Atopic Dermatitis
Jamshida Iqbal Khattak1, Shahzad Rashid Awan2, Saddiq Ullah3, Naseem Ullah4,
Shah zeb5 and Mohammad Sohail1
ABSTRACT
Objective: To find out efficacy of evening primrose oil in treatment of atopic dermatitis.
Study Design: Randomized controlled clinical trial
Place and Duration of Study: This study was conducted at the department of dermatology Mian Rashid Hussain Memorial Hospital Pabbi, Nowshera and Alkhidmat hospital Peshawar for duration of six months from November 2020 to April 2021.
Materials and Methods: Totally, 300 patients were included in the study. Each primrose oil and control group comprise of 150 patients. All the information was recorded at the baseline and each following visit for five months.
Results: All mean values in the evening primrose oil group have gradually and continuously decreased on their 5 successive monthly evaluations in comparison to the baseline values. Intensity and itchiness ratings also declined significantly. In contrast, the average results in the control group have been delayed, less pronounced and uneven. Overall, at the completion of the 5th month, improvement was observed in 147 (98 %) in EPO and 40 (60 %) in control group patients. At any stage of evaluation in either group no major adverse effects were recorded.
Conclusion: Our study concludes that evening primrose oil is effective and safe for the management of atopic dermatitis.
Key Words: Evening primrose oil, Atopic dermatitis, Linoleic acid
Citation of article: Khattak JI, Awan SR, Saddiq Ullah, Naseem Ullah, Shah zeb, Sohail M. Efficacy of Evening Primrose Oil in Treatment of Atopic Dermatitis. Med Forum 2021;32(8):7-11.