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  3. 2.Comparing the Efficacy and Safety of Silodosin versus Extracorporeal Shockwave Lithotripsy for the Management of Lower Ureteric Stone
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2.Comparing the Efficacy and Safety of Silodosin versus Extracorporeal Shockwave Lithotripsy for the Management of Lower Ureteric Stone

Abdul Razaq, Imran Hyder, Ahmad Bilal and Rana Ata ur Rehman

ABSTRACT

Objective: To compare efficacy and safety of Silodosin versus extracorporeal shockwave lithotripsy for the management of lower ureteric stone.

Study Design: Randomized controlled trial

Place and Duration of Study: This study was conducted at the Out Patient Department of Urology, Nishtar Hospital, Multan in 1 year duration from March 2021 to February 2022.

Materials and Methods: A total of 145 patients were enrolled and divided into two groups A and B by lottery method. In group A, patients were given 8 mg oral capsule of silodosin for 28 days and were advised to collect their urine and discontinue Silodosin in case of stone passage. In group B, patients were undergone extracorporeal shockwave lithotripsy (one session weekly for 3 weeks) by a single team with assistance of researcher. SPSS version 23 was used for data analysis.

Results: In silodosin group retrograde ejaculation was noted in 2.9% patients and in ESWL it was noted in 11.4% patients (p-value=0.049). In silodosin group postural hypotension was noted in 4.3% patients and in ESWL it was noted in 15.7% patients (p-value=0.024). In silodosin group dizziness was noted in 1.4% patients and in ESWL bleeding was noted in 5.3% patients (p-value=0.172).

Conclusion: Results of this study reveal that Silodosin is significantly more efficacious and safe drug in terms of outcome as compared to extracorporeal shockwave lithotripsy for the management of lower ureteric stone size of 5-10 mm.

Key Words: Extracorporeal Shockwave Lithotripsy, Silodosin, Lower Ureteric Stone, Stone clearance, Efficacy, Safety

Citation of article: Abdul Razaq, Hyder I, Bilal A, Ata ur Rehman R. Comparing the Efficacy and Safety of Silodosin versus Extracorporeal Shockwave Lithotripsy for the Management of Lower Ureteric Stone. Med Forum 2022;33(11):6-9.