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  3. 29. Frequency of Hyponatremia in Patients with Ischemic Stroke
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29. Frequency of Hyponatremia in Patients with Ischemic Stroke

Sultana Nazeer1, Ayesha Saddique1, Balawal Nazeer1 and Shazia Hayat2


Objectives: Hyponatremia leads to poor clinical outcomes in patients with ischemic stroke, so this study was conducted to evaluate current magnitude of the problem as there is no such study done in Pakistan on this topic.

Study Design: Descriptive study

Place and Duration of Study: This study was conducted at the Department of Medicine, Nishtar Hospital, Multan
from March 2016 to January 2017.

Materials and Methods: One hundred and twenty patients with ischemic stroke were recruited in this descriptive study. The study was conducted at nisthar hospital and duration of this study was three months. Serum Sodium level was checked in these patients and data was analyzed by SPSS – 22.

Results: Out of these 120 patients with ischemic stroke, 88 (73.3%) were male and 32 (26.7%) were female patients and male to female ratio was 2.75:1. Mean age of our study cases was 45.23 ± 14.87 years. Of these 120 patients, 70 (58.3%) were from rural areas, 34 (28.3%) belonged to poor families, 64 (53.3%) were from middle income families and 22 (18.3%) belonged to rich families. Mean body mass index (BMI) was 25.17 ± 3.22 kg/m2 and obesity was noted in 50 (41.7%) patients. History of smoking was present in 66 (55%), diabetes in 52 (43.3%), hypertension in 72 (60%), dyslipidemia in 64 (53.3%) and family history of stroke in 34 (28.3%) patients. Mean serum sodium level was 137.40 ± 9.21 nmol/L (range; 118 nmol/L to 157 nmol/L) and hyponatremia was noted in 48 (40%).

Conclusions: Hyponatremia is a common entity in patients with ischemic stroke as very high frequency was noted in our study. Clinicians treating such patients with ischemic stroke must check this parameter on routine basis  to avoid future adverse clinical outcome and to improve prognosis of the disease. Hyponatremia was significantly associated with history of hypertension.

Key Words: Hyponatremia, ischemic stroke, sodium level.

Citation of article: Nazeer S, Saddique A, Nazeer B, Hayat S. Frequency of Hyponatremia in Patients with Ischemic Stroke. Med Forum 2017;28(4):112-115.