28. Frequency of Intradialytic Hypertension in End Stage Renal Disease Patients on Maintenance Hemodialysis
Zareen Ullah1, Abdul Qadir1, Muhammad Najumu Saqib1, Adam Khan1, Najm-Ud-Din Mufti2 and Muhammad Waheed Sohail1
ABSTRACT
Objective: The primary aim of this investigation is to assess the incidence rate of IDH (Intradialytic hypertension) among patients undergoing dialysis. Additionally, the study aims to identify and analyze different factors that contribute to the enhancement of evidence-based management strategies and clinical outcomes in this context.
Study Design: Cross sectional study
Place and Duration of Study: This study was conducted at the Khyber Teaching Hospital, Nephrology Department in Peshawar, Pakistan from 18th June 2020 to 18th December 2020.
Materials and Methods: After obtaining informed consent, data were prospectively collected from a total of 187 patients who met the predefined diagnostic criteria. Simple descriptive statistics, including mean and standard deviation were used to analyze quantitative data, while for qualitative characteristics, frequency and percentages were used. Chi-square post-stratification analysis was employed and a significance level of p < 0.05 was used.
Results: A total of 187 eligible patients (54% male, 46% female) participated in the study. The mean age of subjects was 39.4 ± 16.5 years, and mean body mass index (BMI) was 22.3 ± 4.9 kg/m2. The duration of hemodialysis varied between 0 and 30 months, with a mean duration of 10.17 ± 6.05 months. Among the participants, 10.1% (n=19) were found to have intra-dialytic hypertension. Of those with intra-dialytic hypertension, 47.3% (n=9) were receiving erythropoiesis-stimulating agent (ESA) treatment. Stratification analysis was carried out to explore the association between intra-dialytic hypertension and various factors.
Conclusion: Intra-dialytic hypertension occurrence is recorded in a substantial group of our local population with end stage renal disease (ESRD). There are few studies on its pathophysiology, risk factors and outcome after treatment in ESRD patients. We suggest further studies to detect the occurrence of intra-dialytic hypertension and its potential outcome as in long term it increasesthe morbidity and mortality.
Key Words: End stage renal disease, hemodialysis, intra-dialytic hypertension