27.Effectiveness of Sequential Peeling as Mono-Therapy for Mild Acne Vulgaris
Sabah Ibad1, Sumeera Zulfiqar1 and Anum Sharif2
ABSTRACT
Objective: Glycolic acid and salicylic acid peels frequently used to treat acne vulgaris. However rarely the two agents are applied as a sequential peel to treat acne vulgaris. The objective of the present study was to reveal the effectiveness of sequential peeling as mono-therapy to treat mild acne vulgaris.
Study design: A randomized control clinical trial study.
Place and Duration of Study: This study was conducted at the Dermatology Department of Combined Military Hospital Multan from July, 2020 to Dec, 2020 for a period of six months.
Methodology: 60 Patients with only mild acne vulgaris who fulfilled inclusion criteria were included in the study. The patients were divided into 3 groups. Group 1 underwent sequential peeling with only 70% Glycolic acid. Group 2 was treated with 30% Salicylic acid. The group 3 received sequential peeling with the combination of glycolic acid and salicylic acid. Acne grading was done by performing lesion count before and after the treatment. Follow up was done to record any worst outcome of the procedure.
Results: 60 patients divided into 3 groups, 20 participants each were included in the study. The course of disease duration ranges from few months to 10 years. 12(60%), 15(75%) & 14(70%) patients in group 1, group 02 and group 3 had skin type III respectively. While 8(40%), 5(25%) and 6(30%) participants had skin type IV in successive groups accordingly. There was a considerable reduction in lesion count after treatment in all 3 groups (p< 0.05). Regarding patient’s satisfaction, the difference between the 3 groups regarding lesion count before and after treatment was not significant. There was also no significant difference in disease duration between 3 groups. However, there was a significant difference regarding patients satisfaction following treatment among 3 groups with P=0.001 for group 03 which is significantly higher than group 01 and 02 both with (P > 0.05).
Conclusion: It was concluded that sequential peeling is an effective treatment to be used as a monotherapy against mild “acne vulgaris”. Moreover, “Glycolic acid” and “salicylic acid” might give improved results while being used in combination.
Keywords: Acne vulgaris, Chemical peels, Glycolic acid, Salicylic acid
Citation of article: Ibad S, Zulfiqar S, Sharif A. Effectiveness of Sequential Peeling as Mono-Therapy for Mild Acne Vulgaris. Med Forum 2021;32(11):111-114.