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Rania Hidayat, Ummarah Raiz, Raees Ahmad, Muhammad Rahim, Adil Naseer and Hafizullah Khan

ABSTRACT

Objective: To determine the prevalence of hepatorenal syndrome in people who had spontaneous bacterial peritonitis and to pinpoint the important clinical and biochemical factors that are related to this condition.

Study Design: A descriptive cross-sectional study

Place and Duration of Study: This study was conducted at the Gastroenterology Unit of Ayub Teaching Hospital from March 2018 to April 2019.

Methods: 113 patients with spontaneous bacterial peritonitis were examined after being admitted to the gastroenterology unit of the Ayub Teaching Hospital. The patients were managed per department protocols for liver cirrhosis (ascites) and spontaneous bacterial peritonitis.

Results: 31 individuals (27.40%) were diagnosed with hepatorenal syndrome (HRS). In comparison to individuals with SBP who did not have HRS, patients with hepatorenal syndrome had considerably lower levels of serum sodium, 24-hour urine sodium, diastolic blood pressure, and mean arterial blood pressure, as well as significantly higher levels of serum creatinine (p = 0.00). Age, sex, the lack of hepatomegaly, and variceal haemorrhage were not associated (p > 0.05).

Conclusion: Patients with SBP often have the deadly consequence of hepatorenal syndrome. Rapid detection and treatment might lower the condition's morbidity and fatality rates.

Key Words: End-stage liver disease, SBP (ascites), Liver Cirrhosis, Hepatorenal Syndrome, Liver transplantation.

Citation of article: Hidayat R, Raiz U, Ahmad R, Rahim M, Naseer A, Khan H. Frequency of Hepatorenal Syndrome in Cirrhotic Patients Presenting with Spontaneous Bacterial Peritonitis. Med Forum 2023;34(10):114-119. doi:10.60110/medforum.341025.