24. Micro and Macrocytic Anemia – A Population Based Cross-Sectional Study
Ayeshah Zaib-Un-Nisa1, Iyad Naeem Muhammad2, Sheikh Abdul Khaliq3 and Agha Umer Draz Khan4
ABSTRACT
Objective: The main objective of current study was to determine age-standardized point prevalence of iron, folic-acid and vitamin B-12 deficiency anemia.
Study Design: A population based cross-sectional study
Place and Duration of Study: This study was conducted at the Department of Pharmacy Practice, Hamdard University and University of Karachi from January-2023 and ended on April-2023.
Methods: Data collected from blood banks. Collected blood samples were analyzed by Hematology Analyzer, Sysmex XP-100 and XN–1000. Analysis of data was done by Statistical Package for Social Sciences version-22. Main outcome measures: Levels of hemoglobin, hematocrit, microcytosis, macrocytosis
Results: Among 8,134 patients and donors data; male 37% (N=3043) and female 63% (N=5091). Age range for the majority of population was 18-28 years. In female; hemoglobin and hematocrit were lower-than normal in 39% (N=1984) and 53% (N=2685) respectively; microcytosis found in 31% (N=1554) and macrocytosis in 7% (N=325). In male; hemoglobin and hematocrit were lower-than normal in 33% (N=994) and 34% (N=1048) respectively; microcytosis reported in 25% (N=739) and macrocytosis in 8% (N=223). In both genders; significant (p=0.0001) differences are noted in the mean values of RBC indices versus the mean value of standard.
Conclusion: Evaluation of data reveals that hypochromic-microcytic anemia highly prevailed in the society. Majority of such population is in between 18-28 years old. Mean values of RBC indices in both gender were significantly lower than standard.
Key Words: Anemia; prevalence; iron; folic-acid; vitamin B-12; microcytosis.
Citation of article: Zaib-Un-Nisa A, Muhammad IN, Khaliq SA, Khan AUD. Micro and Macrocytic Anemia – A Population Based Cross-Sectional Study. Med Forum 2024;35(1):104-108. doi:10.60110/medforum.350123.