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20.Hyperuricemia as a Predictor for the Development of Type 2 Diabetes Mellitus

Syed Saif ur Rehman1, Yasir Mumtaz1, Ayesha Aftab2, Muhammad Wajad Munir1 and Abida Mateen1

ABSTRACT

Objective: Hyperuricemia as a predictor for the development of Type 2 Diabetes Mellitus.

Study Design: Prospective study

Place and Duration of Study: This study was conducted at the Department of Medicine of Al- Nafees Medical College & Hospital, Islamabad from September 2019 to March 2020.

Materials and Methods: The study was conducted after the approval from hospital ethical committee. All the patients were educated and an informed consent was taken. All male and female patients of specified age group presenting to OPD were evaluated. The correlation between hyperuricemia and oral glucose tolerance was based on uric acid level and oral glucose tolerance test from Al-Nafees Medical College and Hospital Laboratory.

Results: A total of 148 patients who fulfilled inclusion criteria were included in this study and divided into two groups of control (Group-1) and cases (Group-2). Group-1 involved 74 controls with a mean age of 51.7 years and Group-2 involved 74 cases with the mean age of 49.2 years. In Group-1 and Group-2 the mean uric acid came out to be 5.53 and 7.9 respectively. In Group-1 and Group-2 mean IGT came out to be 85.8 and 101.9 respectively.

Conclusion: Hyperuricemia is indirectly related to development of diabetes mellitus types 2 as an independent predictor. There should be frequent monitoring of hyperuricemia with oral glucose tolerance test which can help in establishing the undiagnosed cases.

Key Words: Impaired Glucose Tolerance (IGT), Type-2 diabetes mellitus (T2DM), Serum uric acid level (SUA)

Citation of article: Rehman SS, Mumtaz Y, Aftab A, Munir MW, Mateen A. Hyperuricemia as a Predictor for the Development of Type 2 Diabetes Mellitus. Med Forum 2022;33(10):88-91.