20. Effect of Diabetes Mellitus on Corneal Endothelial Cell Count
Rabia Chaudhry, Imran Ali, Naresh Kumar, Nasar Qamar Khan, Wejai Kumar and Kanwal Advani
ABSTRACT
Objective: To determine corneal endothelial cell count in type 2 diabetes mellitus patients.
Study Design: Observational study
Place and Duration of Study: This study was conducted at the Ophthalmology Department, Jinnah Postgraduate Medical Centre, and Karachi from 1st April 2018 to 30th September, 2018.
Materials and Methods: 78 patients of either gender aged between 40 to 60 years who were diagnosed type 2 diabetics and didn’t have any other ocular disease were included in the study. 78 non-diabetic control subjects were also recruited. Patient demographics were documented and corneal endothelial cell count was determined using specular microscopy. Data was analyzed using SPSS version 17.
Results: 156 eyes (78 diabetics and 78 controls) were studied. Mean corneal endothelial cell count was found to be 2051 + 19.039 cells/mm2 and 2580 + 260.3 cells/mm2 in both groups respectively. No association of age and duration of diabetes with corneal endothelial cell count were found.
Conclusion: The corneal endothelial cell count in type 2 diabetics is significantly lower in comparison to healthy subjects.
Key Words: diabetes mellitus, specular microscopy, corneal endothelial cell count
Citation of article: Chaudhry R, Ali I, Kumar N, Khan NQ, Kumar W, Advani K. Effect of Diabetes Mellitus on Corneal Endothelial Cell Count. Med Forum 2019;30(11):76-78.