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  3. 2. Prevalence of Anti Tuberculousis Drug Induced Hepatitis in Patients on Anti Tuberculous Drug in Mardan Medical Complex
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2. Prevalence of Anti Tuberculousis Drug Induced Hepatitis in Patients on Anti Tuberculous Drug in Mardan Medical Complex

Nabi Rehman1, Sajjad Ali1, Shah Zeb2, Muhammad Abbas2, Naveed Khan2 and
Rehman ud Din2

ABSTRACT

Objective: To determine the frequency of anti tuberculousis drugs induced hepatitis in Mardan Medical Complex.

Study Design: Descriptive / cross sectional study

Place and Duration of Study: This study was conducted at the chest OPD and TB centre of Mardan Medical Complex, Mardan from November 2018 to July 2019.

Materials and Methods: Diagnosed 309 cases of TB both pulmonary and extra pulmonary were taken. Among these only category I TB patients were selected and followed up for the development of ATT induced hepatitis.

Results: Study included a total of 309 patients in which 170 (55.01%) were male patients and 139 (44.98%) were female patients. Ages of the patients ranged between 15 and 80 years with a mean age of 34.8 years among male while 14 and 80 years with an mean age of 38.40 years among female. Out of 309 patients only 56 (18.12%) patients developed ATT induced hepatitis.

Conclusion: ATT induced hepatitis is an important and common  side effect of anti tuberculous therapy and needs early recognition and treatment to avoid non compliance to ATT and treatment failure.

Key Words: Hepatitis, ATT, anti tuberculous drugs.

Citation of articles: Rehman N, Ali S, Zeb S, Abbas M, Khan N, Din R. Prevalence of Anti Tuberculousis Drug Induced Hepatitis in Patients on Anti Tuberculous Drug in Mardan Medical Complex. Med Forum 2019;30(8):8-10.