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2. Frequency of Hyperprolactinemia and Hypothyroidism in Infertile Women
Sumbal Andleeb Choudhary1, Syed Saif Ur Rehman2, Rehan Sarwar2, Danish Zia2, Saad Hameed Khan2 and Naheed Fatima1
ABSTRACT
Objective: To determine the frequency of hyperprolactinemia and hypothyroidism in infertile women
Study Design: Descriptive / Cross Sectional study
Place and Duration of Study: This study was conducted at the Department of Obstetrics & Gynecology, Federal Government Services Hospital, Islamabad, from 7th July 2017 to 6th January 2018.
Materials and Methods: After hospital ethical committee approval the study was conducted and informed written consent was taken. All infertile women with duration of marriage >2 years were selected after fulfilling of inclusion criteria between 20 to 40 years and women with pituitary tumor(assessed on medical record), polycystic ovarian disease, known hyperthyroidism and drug history of dopamine depleting, dopamine receptor blocking, H-2 blocker and verapamil intake were excluded. After taking relevant history, an ultrasound abdomen and pelvis was performed. Then 3 ml of blood sample was taken and sent to the institutional pathology laboratory for measuring the serum prolactin levels and serum TSH, T3 & T4 levels. All the data was recorded on a predesigned proforma. Collected information was analyzed by using SPSS 23 version.
Results: Total 72 patients were selected and the age range in this study was from 20 to 40 years with mean age of 29.26 ± 4.65 years. Majority of the patients 37 (51.39%) were between 20 to 30 years of age and mean duration of marriage was 4.17 ± 1.10 years. Hyperprolactinemia in infertile women was found in 22 (30.56%) patients, whereas there was no hyperprolactinemia in 50 (69.44%) patients and Hypothyroidism in infertile women was found in 25 (34.72%) patients, whereas there was no hyperprolactinemia in 47 (65.28%) patients.
Conclusion: This study concluded that frequency of hyperprolactinemia and hypothyroidism in infertile women is quite high. So, we recommend that in every patient of infertile women, hyperprolactinemia and hypothyroidism should be taken into consideration and its early recognition and management should be done in order to reduce the morbidity of the community.
Key Words: Infertility, Hyperprolactinemia, Hypothyroidism
Citation of article: Choudhary SA, Rehman SS, Sarwar R, Zia D, Khan SH, Fatima N. Frequency of Hyperprolactinemia and Hypothyroidism in Infertile Women. Med Forum 2023;34(4):7-11.