2. Association of Sensory Polyneuropathy with Restless Legs Syndrome
Jawwad us Salam1, Akhtar Ali2, Umer Khan2, Mohammad Masroor2, Munir Hussain Siddique3 and Masood Hameed Khan2
ABSTRACT
Objective: To determine the prevalence of restless legs syndrome (RLS) in elderly patients with pure sensory polyneuropathy and correlate the findings with other clinical features. Study Design: Observational / cross sectional study.
Place and Duration of Study: This study was conducted at the Dow University Hospital and Civil Hospital Karachi from 2013 to 2015.
Materials and Methods: 48 patients with Restless leg syndrome were evaluated in our multicenter, prospective study in 2 years for evidence of pure sensory neuropathy either they have demyelinating or axonal type.
Patients were evaluated according age at which symptomsstarted, the severity of symptoms, typical clinical findings and laboratory investigations.
Results: In 21 of the 48 (43.7%) patients, peripheral neuropathy was detected. Ten patients had pure sensory polyneuropathy and remaining have mixed sensory motor polyneuropathy. The pure sensory neuropathy group had comparatively intense and frequent symptoms of Restless leg syndrome. Some of them have family history of Restless leg syndrome. Patients with Mixed sensory motor polyneuropathy did n t have similar strong symptoms of Restless leg syndrome and pain in legs.
Conclusion: The result suggests that Restless leg syndrome is triggered by painful paresthesias is primarilyrelated with pure sensory neuropathy. Patients with mixed sensory motor neur pathy have less intense feature of restless leg syndrome. So the treatment options should be focused on medicines used for neuropathic pain. Key Words: Neuropathy, Restless Leg Syndrome, elderly patients.
Citation of article: Salam J, Ali A, Khan, Masroor M, S ddique MH, Khan MH. Association of Sensory Polyneuropathy with Restless Legs Syndrome. Med Forum 2016;27(6):7-9.