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  3. 1.The Higher Severity Index of Vasomotor Perimenopausal Symptoms Signals the Need to Evaluate Coexisting Metabolic Syndrome for CVD Risk Factors Stratification Experience
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1.The Higher Severity Index of Vasomotor Perimenopausal Symptoms Signals the Need to Evaluate Coexisting Metabolic Syndrome for CVD Risk Factors Stratification Experience

Muhammad Mohsin Rana1, Sajid Rashid Nagra2, Zafar Latif Awan3, Muhammad Saleem Akhtar1, Qasim Rauf4 and Muhammad Wasim Afzal1

ABSTRACT

Objective: To sensitize the general public and medical community about recognizing the association of severity index of perimenopausal syndrome and CHD. Components of MS are preventable through early intervention by lifestyle modification and if needed pharmacotherapy.

Study Design: Observational Cross Sectional study

Place and Duration of Study: This study was conducted at the Rai Medical College Teaching Hospital, Sargodha from June 2022 to March 2023.

Materials and Methods: All perimenopausal patients with the cardinal vasomotor symptoms, between 30-70 years were invited into this study. Recording elements of MS, basic biodata, frequency and severity of VSM perimenopausal symptoms was recorded with the help of trained paramedical staff on the prescribed modified MENQOL proforma. (1, 2 & 4)  The composite score was calculated by multiplying the average weekly occurrence of symptoms with severity score for each symptom.

Results: We had 436 patients during the study period who voluntarily consented and completed the study. We had 49 known diabetics and 191 hypertensives, 30% and 69% in transition and postmenopausal phase for DM and 11%, 18% and 71% respectively for HTN. No underweight female had vasomotor symptom. We had 45 (11%) in early menopausal group, 2.22%, 22.22% and 66.67% was the distribution in different weight categories. We had 101 (24.88%) females in menopausal transition group, 12.87%, 31.68 % and 55.45%) was the distribution. We had 260 (64.15%) females in postmenopausal group, 6.92%, 11.15%, 35.77% and 46.15% was the distribution.

The females having composite severity score between 50 and 75, the distribution was 12, 26, 19 and 35. The females having composite severity score from 76-100, it was 16, 46 and 67. The females having composite severity score above 100, it was 1, 5, 70 and 104. Of the 49 (12%) diabetics, 4% scored 50-75, 26% scored from 76-100 and 69% scored above 100 on composite symptom severity score. Of the 191 hypertensives 11% scored 50-75, 71% scored from 76-100 and 52% scored above 100 on composite symptom severity score.

Conclusion: These factors of metabolic syndrome do cluster around menopause, higher the severity score the higher becomes chances of having CHD. They must be identified and proper interventions at an earlier stage have a preventive and corrective effect on future development of clinically evident CHD

Key Words: peri-menopausal syndromes, vasomotor perimenopausal symptoms, hot flushes

Citation of article: Rana MM, Nagra SR, Awan ZL, Akhtar MS, Rauf Q, Afzal MW. The Higher Severity Index of Vasomotor Perimenopausal Symptoms Signals the Need to Evaluate Coexisting Metabolic Syndrome for CVD Risk Factors Stratification Experience. Med Forum 2023;34(5):2-5.