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  3. 1.Multidrug Resistant- Escherichia Coli – Use of Plant Extracts as Alternative Treatment in Urinary Tract Infection
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1.Multidrug Resistant- Escherichia Coli – Use of Plant Extracts as Alternative Treatment in Urinary Tract Infection

Humaira Arif1, Akhtar Ali1, Muhammad Owais Ismail1, Faisal Iqbal Afridi2, Tanveer Abbas2 and Sehrish Mahmood3

ABSTRACT

Objective: To evaluate the in-vitro antibacterial activity of Moringa Oleifera (MO) and Murraya Koenigii (MK) leaf extracts against Multidrug resistant- Escherichia coli.

Study Design: In-vitro experimental study.

Place and Duration of Study: This study was conducted at the Ziauddin University from December 2022 to
May 2023.

Methods: Extraction of MO and MK leaves was done by using rotary evaporator. Antibacterial activity of both the plants was evaluated by using Broth Dilution assay and Agar well diffusion assay.

Results: Concentrations from 7.812 mg/ml to 500mg/ml were made in 10% DMSO for both the extracts. No significant antibacterial activity was observed against MDR-E. coli at any tested concentration.

Conclusion: MO and MK leaf extracts were found to be inactive against MDR-E. coli isolated from urine samples of UTI.

Key Words: MIC, MDR-E. coli, UTI, Moringa Oleifera, Murraya Koenigii

Citation of article: Arif H, Ali A, Ismail MO, Afridi FI, Abbas T, Mahmood S. Multidrug Resistant- Escherichia coli – Use of Plant Extracts as Alternative Treatment in Urinary Tract Infection. Med Forum 2023;34(11):3-7.doi:10.60110/medforum.341101.