18.Evaluate the Levels of Cardiac Troponin I in Saliva and Serum of Acute Myocardial Infarct Patients
Bhunesha Devi1, Shazia Akbar1, Sana Mubarak1 and Syed Faraz Moin2
ABSTRACT
Objective: The objective of this research was to evaluate the levels of cTnI in saliva between 12-24 hours and correlate the levels of saliva and serum cardiac Troponin I in AMI patients.
Study Design: A cross sectional analytical study
Place and Duration of Study: This study was conducted at the Departments of Cardiology Civil Hospital and Ojha campus Karachi from April, 2021 to August, 2021.
Materials and Methods: Sixty Myocardial infarct patients between the age of thirty to seventy were included in this research. Participants were clinically examined for cardiac and dental complications. Blood and saliva samples were collected between 9 -11 am between 12-24 hours and analyzed by sandwich ELISA technique.
Results: The cTnI was significantly increased in saliva and serum with mean values (0.1609 ng/dl and 14.494 ng/dl in serum) in patients with acute MI. We have positive statistical correlation i.e. spearman roh (r= 0.647) with p-value .001.
Conclusion: Present results reveals positive correlation of Troponin I in saliva and serum which indicates a constant release of troponin I in saliva. Hence, saliva can be used as a noninvasive approach for detection of troponin I at low value in myocardial infarct patients as point of care testing for early and rapid diagnosis.
Key Words: Myocardial infarction, Cardiac troponin-I, Saliva, Serum, ELISA
Citation of article: Devi B, Akbar S, Mubarak S, Moin SF. Evaluate the Levels of Cardiac Troponin I in Saliva and Serum of Acute Myocardial Infarct Patients. Med Forum 2021;32(10):81-85.