18. GBS and AFP (Acute flaccid Paralysis) System in AJK
1. Amjad Mahmood Khan 2. Tariq Mahmood Mughal 3. Abdul Majeed Khan 4. Ehtisham ul Haq 5. Mumtaz Khan
1. Asstt. Prof. of Medicine, 2. Asstt. Prof. of Pathology, 3. Asstt. Prof. of Radiology, MBBS Medical College,
Mirpur AJK and Div; Head Quarter Teaching Hospital Mirpur, AJK. 4. S.O., DHQ Teaching Hospital Mirpur AJK.
5. DHIS Coordinator Mansehra KPK
Objective: Main objective of the study is to highlight the major cause of AFP and % of GBS represents the AFP during the study period.
Study Design: Retrospective analytical study.
Place and Duration of Study: This study was conducted in AJK, for the duration of three years from January 2011 to December 2013.
Materials and Methods: Retrospective analysis of AFP cases reported during 2011-2013. Primarily the AFP cases investigated through history and clinical examination. Principal cause of AFP (Acute flaccid Paralysis) cases were investigated through specific tests like serum electrolytes, CSF (cerebrospinal fluid), electromyogram and viral culture from stool sample to exclude poliovirus. All the cases reported from AJK and taken on the line list labelling as GBS were included in the study during 2011-2013.
Results: Three years data analysis shows more than 50% GBS cases presenting AFP and the numbers are increasing every year. Most of the GBS and even AFP belong to 6-59 months age group. More than 55% GBS cases recover completely and this proportion increased from 2011-2013.
Conclusion: Data analysis revealed GBS is a major cause of AFP in AJK and needs not to be overlooked to keep poliovirus transmission ceased here. AFP surveillance system is huge resource and this is a high time to study all the causes responsible for acute flaccid paralysis to strengthen polio eradication efforts and to develop understanding for prevention and control, to avoid acute flaccid paralysis related morbidity and mortality amongst children in Pakistan. Key Words: GBS, Guillain Barre Syndrome AFP Surveillance, Polio.