17. To Assess the Efficacy of Tranexamic Acid to Prevent Seroma Formation at Donor Site of Latissimus dorsi Flap
Bilal Ahmed Qureshi1, Muhammad Nasarullah2. Husnain Khan1, Ali Adil1, Tayyab Saleem1 and Abdul Malik2
ABSTRACT
Objective: To assess the efficacy of tranexamic acid to prevent seroma formation at donor site of latissimus dorsi flap.
Study Design: Quasi experimental study
Place and Duration of Study: This study was conducted at the Department of Plastic Surgery, Jinnah Burn & Reconstructive Surgery Center/Allama Iqbal Medical College, Lahore from March 2015 to December 2018.
Materials and Methods: Fifty patients who required latissimus dorsi flap for reconstruction were enrolled. After approval from ethical committee, informed consent was taken. Diluted tranexamic acid (20ml of 25mg/ml) was infiltered at the donor site before closure of the wound. Suction drains were placed. 500mg tranexamic acid was given intravenously, thrice daily for 4 days. Ultrasound was performed on second day and after one week of removal of drains to quantify the seroma.
Results: The suction drains showed <30 ml in 15 patients on first post-operative day and were removed on the same day. Two days after drain removal ultrasoundconfirmed35 out of 50 patients showed no seroma on second day while 94% of the patients showed no collection of fluid one week after removal of drains.
Conclusion: Tranexamic acid is highly effective to control the seroma formation over the donor site of latissimus dorsi flap.
Key Words: Tranexamic acid, Latissimus dorsi flap, Seroma
Citation of articles: Qureshi BA, Nasarullah M. Khan H, Adil A, Saleem T, Malik A. To Assess the Efficacy of Tranexamic Acid to Prevent Seroma Formation at Donor Site of Latissimus dorsi Flap. Med Forum 2019;30(2):68-71.