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Sana Arshad¹, Athar Razzaq¹, Ejaz Ahmad¹, Muhammad Ali¹, Muhammad Rashid Shabeer¹ and Kiran Abbas²

ABSTRACT

Objective: To assess the microbiological patterns among neonates suffering from late neonatal sepsis and to specify their antibiotic susceptibility.

Study Design: A retrospective study

Place and Duration of Study: This study was conducted at the Department of Neonatology Department Of Recep Tiyyap Erdogan Hospital Muzafargarh between 1st January 2016 and 1st January 2021.

Materials and Methods: All medical records of neonates who developed or presented after a stay of 48 hours in a hospital setting and presented with signs and symptoms of sepsis and their blood cultures reported between 1st January 2016 and 1st  January 2021 were included in the study. Data was retrieved from REDCap and analyzed by using SPSS version 26.0.

Results: A total of 103 (23.9%) patients' blood cultures were found positive, and of these, 38 (36.3%) were coagulase negative staphylococci, 5 (4.8%) were Actinobacteria, 7(6.8%) were E.coli, 17(16.5%) were Klebsiella pneumoniae, 13(12.62.%) were Pseudomonas aeruginosa, 18 (17.4%) gram positive cocci, 2 (1.94%) were streptococcus, 1(0.97%) proteus vulgaris, 1 (0.97%) MRSA, and 1 (0.97%) were enterococcus species. It is observed that overall microbes show high resistance towards common antimicrobials, including ampicillin, amoxicillin, cefotaxime, tobramycin, and ceftazidime.

Conclusion: The results of this study clearly show that the microbes are resistant to commonly available antibiotics and hence antibiotic stewardship is necessary in resource poor countries like Pakistan.

Key Words: Antibiotic Susceptibility, Neonatal Sepsis, MRSA

Citation of article: Arshad S, Razzaq A, Ahmad E, Ali M, Shabeer MR, Abbas K. Microbiological Patterns Among Neonates Suffering from Late Neonatal Sepsis and to Specify the Antibiotic Susceptibility. Med Forum 2022;33(8):73-77.