1.  Muhammad Atif Ata 2. Hina Atif 3. Shumaila Shabbir Shaikh 4. Muhammad Adeel Ata

1. Asstt. Prof. of Biochemistry, Dow University of Health Sciences, Karachi 2. Medical Officer, Mohammadi Medical Hospital 3. Asstt. Prof. of Biochemistry, University of Hyderabad 4. Lecturer of Chemistry, Cadet College, Petso.

ABSTRACT

Objective: The purpose of present study was to find out the relationship between helicobacter pylori infection and acute myocardial infarction

Study Design: Experimental / Case control study

Place and Duration of Study: This study was carried out the Biochemistry Department, Dow University of Health Sciences, Karachi from 11.02.2013 to 15.12.2013.

Materials and Methods: Serum samples of age and gender matched 80 each of Cardiac and non-cardiac patients with H. Pylori were investigated for the levels of IgG and IgA by kit methods.

RESULTS: Patients who were H.pyloric AMI compared to non-h.pyloric nomal had relationship with increased IgG in Acute myocardial infarction patient with H.pyloric infection as compare to control.

Conclusion: The results of present study suggest that H. pylori is a new risk factor for the development of atherosclerosis and enhance the risk factor. Therefore proper treatment and diagnosis can be helpful for cardiac patients.

Key words: H. pylori, Atherosclerosis, Myocardial infarction, IgG, IgA.