16. Examine the Incidence of Liver Cancer in Patients Presented with Hepatitis B Virus and Hepatitis C Virus Infection
Syed Waseem Ahmad Mujtaba1, Awais Anwar2 and Abdul Matin Qaisar3
ABSTRACT
Objective: To examine the prevalence of hepatocellular carcinoma in hepatitis B virus and hepatitis C virus patients.
Study Design: Prospective study.
Place & Duration of Study: This study was conducted at the Department of Medicine, Amna Inayat Medical College, Sheikhupura from July 2017 to December 2019.
Materials and Methods: One hundred and twenty patients of both genders clinically diagnosed to have Hepatitis B and Hepatitis C virus were included in this study. Patient’s demographical details were recorded. All patients were newly diagnosed and free of hepatocellular carcinoma. All the patients were underwent abdominal ultrasound, computerized tomography scan and AFP at every 6 months for diagnosing hepatocellular carcinoma. Mortality was recorded. Final follow-up was taken at 2 years.
Results: There were 75 (62.5%) male patients while 45 (37.5%) female patients. 25 (20.83%) patients were ages 25 to 40 years, 52 (43.33%) patients were ages 41 to 55 years, 30 (25%) had ages 56 to 70 years and 18 (15%) were above 70 years. 56 (46.67%) patients had Hepatitis B virus and 42 (35%) had hepatitis C virus and 22 (18.33%) had co-infection of hepatitis B virus and hepatitis C virus. Hepatocellular carcinoma was diagnosed in 8 (6.67%) cases at final follow-up. 4 (3.33%) patients were died during the study period.
Conclusion: Prevalence of hepatocellular carcinoma in our study was high. Hepatitis B virus and hepatitis C virus and co-infection considered a major cause for developing hepatocellular carcinoma.
Key Words: Liver cancer, Prevalence, Hepatitis B virus (HBV), Hepatitis C virus (HCV)
Citation of article: Mujtaba SWA, Anwar A, Qaisar AM. Examine the Incidence of Liver Cancer in Patients Presented with Hepatitis B Virus and Hepatitis C Virus Infection. Med Forum 2020;31(2):59-62.