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  3. 14. Frequency of Mortality in Cirrhotic Patients with Acute Variceal Hemorrhage with High MELD (Model for End Stage Liver Disease) Score
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14. Frequency of Mortality in Cirrhotic Patients with Acute Variceal Hemorrhage with High MELD (Model for End Stage Liver Disease) Score

Shahid Karim, Baseer Sultan Ahmad, Perzez Ashraf and Mansoor ul Haq

 

ABSTRACT

 

Objective: To determine the frequency of mortality in cirrhotic patients with acute variceal hemorrhage with high MELD score

Study Design: Observational study

 

Place and Duration of Study: This study was conducted at the Department of Gastroenterology and Hepatology, Liaquat National hospital, Karachi from December 2015 to December 2016.

 

Materials and Methods: Total 193 patients of acute UGI bleeding with cirrhosis were admitted from the period. Patients with hemoglobin <7g/dl were transfused according to individual requirements and resuscitated. Esopghagoduodenoscopy was done to confirm the diagnosis and treat variceal hemorrhage by variceal band ligation for esophageal varices or cyanoacrylate injection in gastric varices within 24 hours of admission. Endoscopy was performed by well experienced and trained Gastroenterologists. Patients MELD score were calculated, those with high MELD score were observed for inhospital mortality. After discharge from hospital patients were followed up in outpatient department for a period of one month.

 

Results: There were 124 male and 69 female patients. The mean age was 45.94±10.44 years. The mean MELD score was 26.19±5.45. Mortality was 16 (8.3%) cases. Among mortality cases, mean MELD score was 27.08±5.46. The association of mortality was found significant with high MELD score.

 

Conclusion: MELD score, if high may be used as a marker for identifying and management of high risk patients of cirrhosis with variceal hemorrhage

Key Words: Mortality, Liver Cirrhosis, MELD Score

 

Citation of articles: Karim S, Ahmad BS, Ashraf P, Haq M. Frequency of Mortality in Cirrhotic Patients with Acute Variceal Hemorrhage with High MELD (Model for End Stage Liver Disease) Score. Med Forum 2017;28(9):53-57.